ESET PROTECT vs SentinelOne: Complete Comparison (2026)
In comparing ESET PROTECT and SentinelOne in 2026, ESET PROTECT is the stronger choice for smbs wanting lightweight, effective endpoint security with central management due to lightweight with low system impact. SentinelOne excels for enterprises wanting ai-driven autonomous endpoint protection and response with autonomous threat response. ESET PROTECT offers Endpoint protection, Cloud sandbox, Full disk encryption starting at $21/device/yr. SentinelOne provides AI-powered endpoint protection, Autonomous response, EDR from $45/endpoint/yr. For teams prioritizing value, ESET PROTECT delivers a hiltonsoftware Score of 74/100. ESET PROTECT and SentinelOne compete in the cybersecurity segment of the SaaS market, where cloud-native solutions, API integrations, and workflow automation drive enterprise and SMB adoption. Other leading cybersecurity tools include Okta, 1Password, Cloudflare. ESET PROTECT serves 400K+ orgs users globally (founded 1992) while SentinelOne reports 12K+ orgs active users (founded 2013).
ESET PROTECT vs SentinelOne at a Glance
What are the main differences between ESET PROTECT and SentinelOne?
ESET PROTECT and SentinelOne differ across ease of use, features, value, support, integrations, scalability, and learning curve. ESET PROTECT leads in 5 of 7 categories.
What are the pros and cons of ESET PROTECT vs SentinelOne?
Which is better, ESET PROTECT or SentinelOne?
After evaluating ESET PROTECT and SentinelOne across features, pricing, integrations, and user satisfaction, ESET PROTECT earns a higher hiltonsoftware Score of 74/100 versus SentinelOne at 69/100. ESET PROTECT stands out for "lightweight with low system impact" and "excellent detection rates". SentinelOne delivers competitive advantages in "autonomous threat response", making SentinelOne a viable alternative.
Neither ESET PROTECT nor SentinelOne offers a free plan. ESET PROTECT starts at $21/device/yr and SentinelOne at $45/endpoint/yr.
Bottom line: Choose ESET PROTECT for smbs wanting lightweight, effective endpoint security with central management. Choose SentinelOne for enterprises wanting ai-driven autonomous endpoint protection and response. Both ESET PROTECT and SentinelOne are established cybersecurity platforms.
SMBs wanting lightweight, effective endpoint security with central management.
Enterprises wanting AI-driven autonomous endpoint protection and response.
ESET PROTECT vs SentinelOne: Frequently Asked Questions
Related Comparisons
Reviewed by Elena Kowalski, Security & Enterprise Editor. Last updated: 2026-04-24. Pricing verified: March 2026.
Read our scoring methodology to understand how the hiltonsoftware Score is calculated.